/* ─── CSS Reset & Variables ───────────────────────────────────── */
*, *::before, *::after { box-sizing: border-box; margin: 0; padding: 0; }

:root {
  --bg:          #0d1117;
  --bg-card:     #161b22;
  --bg-card-2:   #1c2128;
  --border:      #30363d;
  --border-light:#21262d;
  --text:        #e6edf3;
  --text-muted:  #8b949e;
  --text-dim:    #484f58;
  --accent-blue: #58a6ff;
  --accent-green:#3fb950;
  --accent-orange:#d29922;
  --accent-red:  #f85149;
  --accent-purple:#bc8cff;
  --radius:      8px;
  --radius-lg:   12px;
  --shadow:      0 4px 24px rgba(0,0,0,.45);
  --font-mono:   'JetBrains Mono', 'Fira Code', 'Cascadia Code', ui-monospace, monospace;
  --font-sans:   'Inter', system-ui, -apple-system, sans-serif;
  --transition:  0.18s ease;
}

html { font-size: 15px; scroll-behavior: smooth; }
body {
  background: var(--bg);
  color: var(--text);
  font-family: var(--font-sans);
  line-height: 1.6;
  min-height: 100vh;
}

/* ─── Site Header ─────────────────────────────────────────────── */
.site-header {
  background: linear-gradient(135deg, #0d1117 0%, #161b22 100%);
  border-bottom: 1px solid var(--border);
  padding: 1.5rem 2rem;
}
.header-inner { max-width: 1400px; margin: 0 auto; }

.logo {
  display: flex;
  align-items: center;
  gap: .6rem;
  margin-bottom: .25rem;
}
.logo-icon  { font-size: 1.6rem; }
.logo-text  { font-size: 1.35rem; font-weight: 700; color: var(--text); letter-spacing: -.02em; }
.logo-badge {
  background: linear-gradient(90deg, #1f6feb, #388bfd);
  color: #fff;
  font-size: .68rem;
  font-weight: 600;
  padding: .18rem .55rem;
  border-radius: 100px;
  letter-spacing: .03em;
}
.header-sub { font-size: .82rem; color: var(--text-muted); }

/* ─── Layout ──────────────────────────────────────────────────── */
.main-content {
  max-width: 1400px;
  margin: 2rem auto;
  padding: 0 1.5rem;
  display: flex;
  flex-direction: column;
  gap: 1.25rem;
}

.card {
  background: var(--bg-card);
  border: 1px solid var(--border);
  border-radius: var(--radius-lg);
  padding: 1.5rem;
  box-shadow: var(--shadow);
}

.panel-title {
  font-size: 1rem;
  font-weight: 600;
  color: var(--text);
  display: flex;
  align-items: center;
  gap: .5rem;
}

/* ─── Query Panel ─────────────────────────────────────────────── */
.query-panel { }

.search-row {
  display: flex;
  align-items: flex-end;
  gap: .85rem;
  flex-wrap: wrap;
  margin-top: 1rem;
}

.field-group {
  display: flex;
  flex-direction: column;
  gap: .3rem;
  flex: 1;
  min-width: 160px;
}
.field-group label {
  font-size: .75rem;
  font-weight: 600;
  color: var(--text-muted);
  text-transform: uppercase;
  letter-spacing: .06em;
}
.field-group input {
  background: var(--bg);
  border: 1px solid var(--border);
  border-radius: var(--radius);
  color: var(--text);
  font-family: var(--font-mono);
  font-size: .9rem;
  padding: .55rem .85rem;
  outline: none;
  transition: border-color var(--transition), box-shadow var(--transition);
}
.field-group input::placeholder { color: var(--text-dim); }
.field-group input:focus {
  border-color: var(--accent-blue);
  box-shadow: 0 0 0 3px rgba(88,166,255,.15);
}

.btn-primary {
  display: flex;
  align-items: center;
  gap: .4rem;
  background: var(--accent-blue);
  color: #0d1117;
  border: none;
  border-radius: var(--radius);
  font-size: .88rem;
  font-weight: 700;
  padding: .57rem 1.35rem;
  cursor: pointer;
  transition: background var(--transition), transform var(--transition);
  white-space: nowrap;
}
.btn-primary:hover  { background: #79c0ff; transform: translateY(-1px); }
.btn-primary:active { transform: translateY(0); }
.btn-primary:disabled { opacity: .5; cursor: not-allowed; transform: none; }

.btn-ghost {
  background: transparent;
  color: var(--text-muted);
  border: 1px solid var(--border);
  border-radius: var(--radius);
  font-size: .85rem;
  font-weight: 500;
  padding: .55rem 1rem;
  cursor: pointer;
  transition: color var(--transition), border-color var(--transition);
}
.btn-ghost:hover { color: var(--text); border-color: var(--text-muted); }

/* ─── Status Bar ──────────────────────────────────────────────── */
.status-bar {
  margin-top: .9rem;
  font-size: .82rem;
  min-height: 1.4rem;
  color: var(--text-muted);
}
.status-bar.loading { color: var(--accent-blue); }
.status-bar.success { color: var(--accent-green); }
.status-bar.error   { color: var(--accent-red); }
.status-bar.empty   { color: var(--accent-orange); }

/* ─── Results Table ───────────────────────────────────────────── */
.results-section { }

.results-header {
  display: flex;
  align-items: center;
  justify-content: space-between;
  flex-wrap: wrap;
  gap: .6rem;
  margin-bottom: 1rem;
}

.badge {
  background: var(--accent-blue);
  color: #0d1117;
  font-size: .72rem;
  font-weight: 700;
  padding: .15rem .55rem;
  border-radius: 100px;
}

.track-legend {
  display: flex;
  align-items: center;
  gap: .5rem;
  font-size: .78rem;
  color: var(--text-muted);
}
.legend-dot {
  display: inline-block;
  width: 10px; height: 10px;
  border-radius: 50%;
}
.dot-alpha  { background: #58a6ff; }
.dot-svm    { background: #d29922; }
.dot-vcf    { background: #3fb950; }

.table-wrap {
  overflow-x: auto;
  border-radius: var(--radius);
  border: 1px solid var(--border-light);
}

table {
  width: 100%;
  border-collapse: collapse;
  font-size: .83rem;
}
thead { background: var(--bg-card-2); }
th {
  padding: .6rem .9rem;
  text-align: left;
  font-weight: 600;
  color: var(--text-muted);
  font-size: .75rem;
  text-transform: uppercase;
  letter-spacing: .06em;
  white-space: nowrap;
  border-bottom: 1px solid var(--border);
}
.th-note { font-weight: 400; font-size: .68rem; color: var(--text-dim); }

td {
  padding: .55rem .9rem;
  border-bottom: 1px solid var(--border-light);
  color: var(--text);
  white-space: nowrap;
  font-family: var(--font-mono);
  font-size: .82rem;
}
tbody tr:last-child td { border-bottom: none; }
tbody tr:hover { background: var(--bg-card-2); }

.td-chr     { color: var(--accent-purple); }
.td-pos     { color: var(--text-muted); }
.td-gene    { color: var(--accent-blue); font-weight: 600; }
.td-receptor{ color: var(--accent-orange); }
.td-csq     { color: var(--text-muted); font-family: var(--font-sans); font-size: .78rem; }
.td-alpha   { color: #79c0ff; }
.td-svm     { color: #e3b341; }
.td-af      { color: var(--text-muted); }
.score-bar  {
  display: inline-block;
  height: 6px;
  border-radius: 3px;
  vertical-align: middle;
  margin-right: 4px;
}

/* ─── Significance Pills ──────────────────────────────────────── */
.sig-pill {
  display: inline-block;
  padding: .15rem .5rem;
  border-radius: 4px;
  font-size: .72rem;
  font-weight: 600;
  font-family: var(--font-sans);
}
.sig-path   { background: rgba(248,81,73,.18); color: #f85149; }
.sig-likely { background: rgba(210,153,34,.18); color: #d29922; }
.sig-benign { background: rgba(63,185,80,.18);  color: #3fb950; }
.sig-vus    { background: rgba(139,148,158,.15); color: #8b949e; }

/* ─── IGV Section ─────────────────────────────────────────────── */
.igv-section { }
.igv-header {
  display: flex;
  align-items: center;
  gap: .75rem;
  flex-wrap: wrap;
  margin-bottom: 1rem;
}
.locus-badge {
  background: rgba(88,166,255,.12);
  border: 1px solid rgba(88,166,255,.35);
  color: var(--accent-blue);
  font-family: var(--font-mono);
  font-size: .78rem;
  padding: .2rem .65rem;
  border-radius: 6px;
}
.igv-track-info {
  display: flex;
  gap: .4rem;
  flex-wrap: wrap;
  margin-left: auto;
}
.track-pill {
  font-size: .72rem;
  font-weight: 600;
  padding: .2rem .6rem;
  border-radius: 100px;
  font-family: var(--font-sans);
}
.pill-blue   { background: rgba(88,166,255,.18); color: #79c0ff; }
.pill-orange { background: rgba(210,153,34,.18); color: #e3b341; }
.pill-green  { background: rgba(63,185,80,.18);  color: #56d364; }

#igv-container {
  min-height: 420px;
  background: #0a0e13;
  border-radius: var(--radius);
  border: 1px solid var(--border-light);
  overflow: hidden;
}

/* igv.js 內部顏色覆寫 */
#igv-container .igv-app-container { background: #0a0e13; }

/* ─── Footer ──────────────────────────────────────────────────── */
.site-footer {
  text-align: center;
  padding: 1.5rem;
  font-size: .78rem;
  color: var(--text-dim);
  border-top: 1px solid var(--border-light);
  margin-top: 2rem;
}
.site-footer code {
  font-family: var(--font-mono);
  color: var(--text-muted);
  background: var(--bg-card);
  padding: .1rem .35rem;
  border-radius: 4px;
}

/* ─── OOM 斷路器警告橫幅 ────────────────────────────────────────── */
.warning-banner {
  display: flex;
  align-items: flex-start;
  gap: .75rem;
  margin-top: 1rem;
  padding: .85rem 1.1rem;
  background: rgba(210,153,34,.10);
  border: 1px solid rgba(210,153,34,.45);
  border-left: 4px solid var(--accent-orange);
  border-radius: var(--radius);
  font-size: .83rem;
  line-height: 1.55;
  color: #e3b341;
  animation: slideDown .22s ease;
}
.warning-banner .wb-icon { font-size: 1.2rem; flex-shrink: 0; margin-top: .05rem; }
.warning-banner .wb-body { flex: 1; }
.warning-banner .wb-title {
  font-weight: 700;
  font-size: .88rem;
  margin-bottom: .25rem;
  color: #f0c060;
}
.warning-banner .wb-reason {
  font-size: .78rem;
  color: rgba(224,175,80,.75);
  margin-top: .2rem;
  font-family: var(--font-mono);
}
.warning-banner .wb-action {
  margin-top: .4rem;
  font-size: .78rem;
  color: rgba(224,175,80,.9);
}
.warning-banner .wb-action strong { color: #f0c060; }

@keyframes slideDown {
  from { opacity: 0; transform: translateY(-6px); }
  to   { opacity: 1; transform: translateY(0); }
}

/* pill-red（降級模式標籤） */
.pill-red { background: rgba(248,81,73,.18); color: #ff7b72; }

/* ─── Spinner ─────────────────────────────────────────────────── */
@keyframes spin { to { transform: rotate(360deg); } }
.spinner {
  display: inline-block;
  width: 12px; height: 12px;
  border: 2px solid var(--border);
  border-top-color: var(--accent-blue);
  border-radius: 50%;
  animation: spin .7s linear infinite;
  vertical-align: middle;
  margin-right: 6px;
}

/* ─── Responsive ──────────────────────────────────────────────── */
@media (max-width: 700px) {
  .search-row { flex-direction: column; }
  .btn-primary, .btn-ghost { width: 100%; justify-content: center; }
  .igv-header { flex-direction: column; align-items: flex-start; }
  .igv-track-info { margin-left: 0; }
}

/* ─── IGV 暗黑模式強制覆蓋 (Dark Mode Overrides) ──────────────── */

/* 1. 主容器與背景黑化 */
.igv-container,
.igv-track-container,
.igv-column-container {
  background-color: #111827 !important;
  border: none !important;
}

/* 2. 頂部導覽列與捲軸暗化 */
.igv-navbar {
  background-color: #1f2937 !important;
  border-bottom: 1px solid #374151 !important;
}
.igv-navbar * {
  color: #d1d5db !important;
}

/* 3. 拯救隱形的軌跡標籤 (Track Labels) */
.igv-track-label {
  background-color: rgba(31, 41, 55, 0.85) !important;
  color: #f3f4f6 !important;
  border: 1px solid #4b5563 !important;
  border-radius: 4px !important;
  padding: 4px 8px !important;
  font-weight: 600 !important;
}

/* 4. 消除左右白色側邊欄（Y 軸 & 齒輪圖示區域） */
.igv-data-axis,
.igv-left-hand-gutter,
.igv-right-hand-gutter,
.igv-track-manipulation-handle {
  background-color: #1f2937 !important;
  border-color: #374151 !important;
}

/* 5. Y 軸刻度數字：將白底黑字 canvas 反轉為暗底亮字 */
.igv-data-axis canvas {
  filter: invert(1) hue-rotate(180deg);
}

/* 6. 軌跡分隔線 */
.igv-track-div {
  border-bottom: 1px solid #374151 !important;
}